Hello Will,

The issue happens because you should do a postback in order to make the changes have effect.

I can suggest you two options:

1) When you set the WebPanel to be enabled you should iterate through the controls and enable them

For example:

        function WebDropDown1_SelectionChanging(sender, eventArgs) { 

            var text = eventArgs.getNewSelection()[0].get_text();

            var panel = igpnl_getPanelById('WebPanel1');

            var chooser = igdrp_getComboById("<% =WebDateChooser1.ClientID %>");

            if (text == "Enabled") {

                panel.setEnabled(true);

                chooser.setEnabled(true);

            }

            else {

                panel.setEnabled(false);

                chooser.setEnabled(false);

            }

        }

2) Wrap the Controls inside update panel and turn on the AutoPostBackFlags-SelectionChanged  of the WebDropDown

        <asp:UpdatePanel ID="UpdatePanel1" runat="server">

            <ContentTemplate>

                <ig:WebDropDown ID="WebDropDown1" runat="server" Width="200px" OnSelectionChanged="WebDropDown1_SelectionChanged">

                    <Items>

                        <ig:DropDownItem Selected="False" Text="Enabled" Value="">

                        </ig:DropDownItem>

                        <ig:DropDownItem Selected="False" Text="Disabled" Value="">

                        </ig:DropDownItem>

                    </Items>

                    <AutoPostBackFlags SelectionChanged="On" />

                    <ClientEvents SelectionChanging="WebDropDown1_SelectionChanging" />

                </ig:WebDropDown>

                <igmisc:WebPanel ID="WebPanel1" runat="server">

                    <Template>

                        <igsch:WebDateChooser ID="WebDateChooser1" runat="server">

                        </igsch:WebDateChooser>

                        <asp:TextBox ID="TextBox1" runat="server"></asp:TextBox>

                        <ig:WebCaptcha ID="WebCaptcha1" runat="server" Width="250px">

                        </ig:WebCaptcha>

                        <asp:RadioButtonList ID="RadioButtonList1" runat="server">

                            <asp:ListItem>1</asp:ListItem>

                            <asp:ListItem>2</asp:ListItem>

                            <asp:ListItem>3</asp:ListItem>

                        </asp:RadioButtonList>

                    </Template>

                </igmisc:WebPanel>

            </ContentTemplate>

        </asp:UpdatePanel>

Please let me know if you need further assistance regarding this.

Tsvetelina, the 2nd option of making sure all controls are wrapped in an UpdatePanel worked for me.  Thanks so much!