Hi Hemant,

Thank you for posting in our forum.

 If you want to change the value on the server, you should change the value in the DataSource and rebind the second grid in the first grid's RowUpdating event. Alternatively, you could handle ExitedEditMode client-side event to set new value for a cell in the second grid like this:

function ExitedEditModeHandler(sender, eventArgs)

{    

    var grid = $find("WebDataGrid2");    

    grid.get_rows().get_row(1).get_cell(1).set_value("value");

}

After postback the grid value will be updated in the DataSource.

Let me know if you have any questions.