Hi, 

Sure thats no problem. 

Basically you just need to create a custom column and custom cell. In the code below they are ButtonColumn and ButtonCell. With the button, i use the AddTarget option and use a selector. You need to make sure you mark the method you want to invoke with an Export that matches the name of the selector though. I've highlighted the code below: 

public class ButtonCell : IGGridViewCell
    {
        UIButton _button;

        public ButtonCell(string id) :base(id)
        {
            _button = new UIButton (UIButtonType.RoundedRect);
            _button.AddTarget(this, new MonoTouch.ObjCRuntime.Selector("Clicked"), UIControlEvent.TouchUpInside);
            this.AddSubview (_button);
        }

        [Export("Clicked")]
        public void Clicked()
        {
            _button.SetTitle ("Pressed", UIControlState.Normal);
        }

        public void SetText(string text)
        {
            _button.SetTitle (text, UIControlState.Normal);
        }

        public override void SetupSize (SizeF size)
        {
            _button.Frame = new RectangleF (0, 0, size.Width, size.Height);
        }

    }

    public class ButtonColumn : IGGridViewColumnDefinition
    {
        public ButtonColumn()
        {

        }

        public override string FieldKey {
            get {
                return "BC";
            }
        }

        public override IGGridViewCell CreateCell (IGGridView gridView, IGCellPath path, IGGridViewDataSourceHelper dataSource)
        {
            ButtonCell cell = (ButtonCell)gridView.DequeueReusableCell ("BC");
            if (cell == null) {
                cell = new ButtonCell ("BC");
            }

            cell.SetText ("PUSH");

            return cell;
        }

    }

Hope this helps, 

-SteveZ