okay so in a typical gridview (Microsoft ASP.net one) you can put a drop down list in a template column, then in the selectedindexchanged event you can type this

    Protected Sub ddl_PackWeek_SelectedIndexChanged(ByVal sender As System.Object, ByVal e As System.EventArgs)

        Dim gd_data1 As New DataAccessLayer()

        'get dropdownlist object
        Dim Myddl As DropDownList = CType(sender, DropDownList)

        'use naming container property to get the row in which the control resides
        Dim MyRow As GridViewRow = CType(Myddl.NamingContainer, GridViewRow)

'database call
        gd_data1.updatePackWeek(MyRow.Cells(0).Text, Myddl.SelectedItem.Value)

        Me.gv_receiving.DataBind()
    End Sub

How do you do this in a web grid view?

in so many words, how do I access info from the ROW of my Drop Down List?

ASP if you need it

                                         <ig:TemplateDataField Header-Text ="Pack Type" key="BoxType2" Width="200px">
                                         <ItemTemplate>
                                              <asp:DropDownList ID="DropDownList2" runat="server" AutoPostBack="True" OnSelectedIndexChanged="ddl_BoxesType2_SelectedIndexChanged"
                                                 SelectedValue='<%# Bind("BoxType2")%>' DataSourceID="sqlBoxesType2" DataTextField="BoxType2_SN" DataValueField="RecID">
                                             </asp:DropDownList>
                                         </ItemTemplat<Header Text="Pack Type"></Header>
                                         </ig:TemplateDataField>