For the ribbon

We are using Infragistics together with Prism 4.1 and it works, just use attached properties to bind a contenthost to a regionmanager.

And ofcourse write a RegionAdapter for the Ribbon.

Our shell window:

<igRibbon:XamRibbonWindow x:Class="Shell"
    xmlns="http://schemas.microsoft.com/winfx/2006/xaml/presentation"
    xmlns:x="http://schemas.microsoft.com/winfx/2006/xaml"
    xmlns:cal="http://www.codeplex.com/CompositeWPF"    
    xmlns:igDock="http://infragistics.com/DockManager"
    xmlns:igRibbon="http://infragistics.com/Ribbon"                          
    Title="Title" WindowState="Maximized" Closing="XamRibbonWindow_Closing">
        
    <igRibbon:RibbonWindowContentHost cal:RegionManager.RegionName="MenuRegion">
        <igRibbon:RibbonWindowContentHost.StatusBar>
            <StatusBar Name="StatusBar1">
                <StatusBar.ItemsPanel>
                    <ItemsPanelTemplate>
                        <Grid>
                            <Grid.RowDefinitions>
                                <RowDefinition Height="*"></RowDefinition>
                            </Grid.RowDefinitions>
                            <Grid.ColumnDefinitions>
                                <ColumnDefinition Width="*"></ColumnDefinition>
                                <ColumnDefinition Width="Auto"></ColumnDefinition>
                            </Grid.ColumnDefinitions>
                        </Grid>
                    </ItemsPanelTemplate>
                </StatusBar.ItemsPanel>
                <StatusBarItem Grid.Column="0">
                    <TextBlock x:Name="txtVersion" Margin="5" HorizontalAlignment="Right"></TextBlock>
                </StatusBarItem>
                <StatusBarItem Grid.Column="1">
                    <TextBlock x:Name="txtIngelogdeGebruiker" Margin="5" HorizontalAlignment="Right"></TextBlock>
                </StatusBarItem>
            </StatusBar>
        </igRibbon:RibbonWindowContentHost.StatusBar>
  
        <Grid Background="{DynamicResource BackgroundBrush}">
            <Grid.RowDefinitions>
                <RowDefinition Height="*"></RowDefinition>
            </Grid.RowDefinitions>
        
            <igDock:XamDockManager Grid.Row="0" x:Name="dockingManager" 
                                   Margin="0,0,0,0"
                                   VerticalAlignment="Stretch"
                                   NavigationOrder="VisibleOrder"
                                   >
                <!-- The Panes collection is collection used to create the 
         root split pane that contain the floating, docked and 
         unpinned content panes -->
                <igDock:XamDockManager.Panes>
 
                    <igDock:SplitPane igDock:XamDockManager.InitialLocation="DockedLeft"
                                      SplitterOrientation="Horizontal"
                                      Height="{Binding Path=ActualHeight, ElementName=dockingManager, Mode=OneWay}"
                                      Width="{Binding Path=ActualWidth, ElementName=dockingManager, Mode=OneWay}"
                                      >
                        <igDock:TabGroupPane cal:RegionManager.RegionName="LeftRegion"
                                             HorizontalContentAlignment="Stretch"
                                             VerticalContentAlignment="Stretch">
                        </igDock:TabGroupPane>
                    </igDock:SplitPane>
                    
                    <igDock:SplitPane igDock:XamDockManager.InitialLocation="DockedBottom"
                          SplitterOrientation="Vertical">
                        <igDock:TabGroupPane cal:RegionManager.RegionName="BottomRegion"
                                             Height="200"
                                             HorizontalContentAlignment="Stretch"
                                             VerticalContentAlignment="Stretch">
                        </igDock:TabGroupPane>
                    </igDock:SplitPane>
                </igDock:XamDockManager.Panes>
 
                <igDock:DocumentContentHost>
                    <!-- a document content host contains 1 or more split panes -->
                    <igDock:SplitPane>
                        <!-- those split panes can only contain a tabgrouppane -->
                        <igDock:TabGroupPane Name="WorkRegion"
                                             cal:RegionManager.RegionName="WorkRegion" 
                                             HorizontalContentAlignment="Stretch"
                                             VerticalContentAlignment="Stretch">
                        </igDock:TabGroupPane>
                    </igDock:SplitPane>
                </igDock:DocumentContentHost>
                
            </igDock:XamDockManager>
        </Grid>
    </igRibbon:RibbonWindowContentHost>
</igRibbon:XamRibbonWindow>

and our adapter

 
    public class RibbonWindowContentHostRegionAdapter : RegionAdapterBase<RibbonWindowContentHost>, IRibbonWindowContentHostRegionAdapter
    {     
        private XamRibbon FindRibbonOnView(object view)
        {
            DependencyObject viewAsDependency = view as DependencyObject;
            if (viewAsDependency == null)
            {
                return null;
            }
            IEnumerable children = LogicalTreeHelper.GetChildren(viewAsDependency);
            foreach (object child in children)
            {
                if (typeof(XamRibbon).IsAssignableFrom(child.GetType()))
                {
                    return child as XamRibbon;
                }
                XamRibbon result = FindRibbonOnView(child);
                if (result != null)
                {
                    return result;
                }
            }
            return null;
        }
 
        public RibbonWindowContentHostRegionAdapter(IRegionBehaviorFactory regionBehaviorFactory)
            : base(regionBehaviorFactory)
        {
        }
 
        protected override void Adapt(IRegion region, RibbonWindowContentHost regionTarget)
        {
            bool contentIsSet = regionTarget.Ribbon != null;
            if (contentIsSet)
            {
                throw new InvalidOperationException("Only a single instance of the Ribbon is allowed on the host.");
            }
 
            region.Views.CollectionChanged +=
                (sender, e) =>
                {
                    if (e.Action == NotifyCollectionChangedAction.Add && region.ActiveViews.Count() == 0)
                    {
                        XamRibbon menu = FindRibbonOnView(region.Views.FirstOrDefault());
                        if (menu == null)
                        {
                            throw new InvalidOperationException("No XamRibbon found in view.");
                        }
                        else if (typeof(Panel).IsAssignableFrom(menu.Parent.GetType()))
                        {
                            (menu.Parent as Panel).Children.Remove(menu);
                            regionTarget.Ribbon = menu;
                            region.Activate(e.NewItems[0]);
                        }
                        else
                        {
                            throw new InvalidOperationException("Parent of the XamRibbon must be a Panel.");
                        }
                    }
                };
        }
 
        protected override IRegion CreateRegion()
        {
            return new SingleActiveRegion();
        }
    }
}

In the bootstrapper register the adapter for the RibbonWindowContentHost

             regionAdapterMappings.RegisterMapping(typeof(RibbonWindowContentHost), Container.Resolve<RibbonWindowContentHostRegionAdapter>());